About me
I am an AI for Life Science researcher at the Lotfollahi Lab, Wellcome Sanger Institute, working at the intersection of machine learning and biomedical science.
I see myself as a problem finder as much as a problem solver. My background in bioinformatics and biochemistry leads me to look for gaps where existing computational approaches fall short. Rather than simply applying established AI frameworks to biology, I focus on identifying under-explored problems in the domain and developing novel solutions to address the problems. I translate the complexity of biological and medical questions into well-defined computational problems, then build the models needed to solve them.
💡 Research Interest
- Multi-modal learning of biomedical images and spatial transcriptomics
- Regulatory DNA sequence generation
- Temporal cell dynamics modeling
🚩 Research Vision
“What I cannot create, I do not understand” — Richard Feynman
I was drawn to computational biology by the idea that DNA is the ultimate code: a sequence in which both code and the codebook are deeply entangled. My research ambition is to build a program that can simulate biological systems from DNA sequence.
🔥 News
- 🎉 Sep 2026 · LocoGen, a locality-aware generative model for designing regulatory DNA, was accepted to NeurIPS 2026.
- 🎉 Jul 2026 · Selected as one of 500 participants from over 6,000 applicants in the Anthropic × Gladstone Claude Life Sciences Hackathon, where I built a generative model that infers missing cell states across time points (LinkedIn post).
- 🎉 Jun 2026 · SIGMMA was accepted to the ICML FM4LS/SD4H workshop; a journal version is in preparation (manuscript).
- 🎉 Oct 2024 · Joined the Wellcome Sanger Institute.
💼 Professional Experience
Senior Data Scientist · Wellcome Sanger Institute, UK · Oct 2024 – present
- Led SIGMMA, a hierarchical contrastive learning framework aligning H&E histopathology with spatial transcriptomics (ICML 2026 workshop paper; journal version in preparation)
- Led LocoGen, a generative framework for de novo regulatory DNA design that uses property-guided generation for out-of-distribution objectives in a lab-in-the-loop cycle (NeurIPS 2026)
Research Intern · LG AI Research, Korea · Jan – Apr 2024
- Contributed to ExaonePath, a self-supervised foundation model for H&E histopathology images (press)
- Built a scalable, reproducible multi-omics preprocessing pipeline
🧬 Projects
🔬 Spatial transcriptomics × histopathology
- SIGMMA · Lead · 2025 – present
Hierarchical contrastive learning aligning H&E histopathology with spatial transcriptomics.
ICML 2026 workshop · journal version in preparation - ExaonePath · Contributor · 2024, LG AI Research
Self-supervised foundation model for H&E histopathology images.
press
🧬 Regulatory DNA generation
- LocoGen · Lead · 2025 – present
Generative framework for de novo regulatory DNA design that uses property-guided generation for out-of-distribution objectives in a lab-in-the-loop cycle.
NeurIPS 2026
⏱️ Temporal cell dynamics
- Cell-state inference across time · 2026, Anthropic × Gladstone Hackathon
A generative model that infers missing cell states across time points.
LinkedIn post
🧪 Multi-omics biomarker discovery
- GOAT · Lead · PhD
Graph neural network for multi-omics biomarker discovery in eosinophilic asthma.
Bioinformatics, 2023 - VWA5A as a biomarker in breast cancer · Co-author · PhD
Machine-learning-based protein prioritization identifying VWA5A as a prognostic marker for breast-cancer metastasis.
Scientific Reports, 2024 - Patent (Korea) · Co-inventor
Multi-omics biomarker discovery method, registered through the Korean Intellectual Property Office.
KIPRIS
🎓 Education
Ph.D., Interdisciplinary Program of Bioinformatics · Seoul National University, Korea · Sep 2018 – Aug 2024
- Thesis: Computational modeling of molecular interactions for biomarker discovery using single/multi-omics data
- 3 first-authored and 10 co-authored papers
- Developed GOAT, a graph neural network for multi-omics biomarker discovery in eosinophilic asthma (Bioinformatics, 2023)
- Developed RNA-seq quantification and normalization pipelines for ICGC-ARGO
B.S., Biochemistry · Yonsei University, Korea · Mar 2013 – Aug 2018